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1Regulation of Golgi structure and secretion by receptor-induced G protein βγ complex translocation by Deepak Kumar Saini and othersregulation-of-golgi-structure-and-secretion-by-receptor-induced-g-protein-beta-gamma-complex-translocation-by-deepak-kumar-saini-and-others2026-10-202026-10-20
1Crystal structures of a multidrug transporter reveal a functionally rotating mechanism by Satoshi Murakami and otherscrystal-structures-of-a-multidrug-transporter-reveal-a-functionally-rotating-mechanism-by-satoshi-murakami-and-others2026-10-202026-10-20
1Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop by Thomas Eicher and otherstransport-of-drugs-by-the-multidrug-transporter-acrb-involves-an-access-and-a-deep-binding-pocket-that-are-separated-by-a-switch-loop-by-thomas-eicher-and-others2026-10-202026-10-20
1Homeoviscous adaptation—a homeostatic process that regulates the viscosity of membrane lipids in Escherichia coli by Michael Sinenskyhomeoviscous-adaptation-a-homeostatic-process-that-regulates-the-viscosity-of-membrane-lipids-in-escherichia-coli-by-michael-sinensky2026-10-202026-10-20
1Separation of liquid phases in giant vesicles of ternary mixtures of phospholipids and cholesterol by Sarah L. Veatch and Sarah L. Kellerseparation-of-liquid-phases-in-giant-vesicles-of-ternary-mixtures-of-phospholipids-and-cholesterol-by-sarah-l-veatch-and-sarah-l-keller2026-10-202026-10-20
1Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape by Joseph H. Lorent and othersplasma-membranes-are-asymmetric-in-lipid-unsaturation-packing-and-protein-shape-by-joseph-h-lorent-and-others2026-10-202026-10-20
1Conformational biosensors reveal GPCR signalling from endosomes by Roshanak Irannejad and othersconformational-biosensors-reveal-gpcr-signalling-from-endosomes-by-roshanak-irannejad-and-others2026-10-202026-10-20
1Deciphering the splicing code by Yoseph Barash and othersdeciphering-the-splicing-code-by-yoseph-barash-and-others2026-10-202026-10-20
1An RNA map predicting Nova-dependent splicing regulation by Jernej Ule and othersan-rna-map-predicting-nova-dependent-splicing-regulation-by-jernej-ule-and-others2026-10-202026-10-20
1N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions by Nian Liu and othersn6-methyladenosine-dependent-rna-structural-switches-regulate-rna-protein-interactions-by-nian-liu-and-others2026-10-202026-10-20
1Thiol-linked alkylation of RNA to assess expression dynamics by Veronika A. Herzog and othersthiol-linked-alkylation-of-rna-to-assess-expression-dynamics-by-veronika-a-herzog-and-others2026-10-202026-10-20
1Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation by Huilin Huang and othersrecognition-of-rna-n6-methyladenosine-by-igf2bp-proteins-enhances-mrna-stability-and-translation-by-huilin-huang-and-others2026-10-202026-10-20
1Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers by Leighton J. Core and othersanalysis-of-nascent-rna-identifies-a-unified-architecture-of-initiation-regions-at-mammalian-promoters-and-enhancers-by-leighton-j-core-and-others2026-10-202026-10-20
1The human initiator is a distinct and abundant element that is precisely positioned in focused core promoters by Long Vo ngoc and othersthe-human-initiator-is-a-distinct-and-abundant-element-that-is-precisely-positioned-in-focused-core-promoters-by-long-vo-ngoc-and-others2026-10-202026-10-20
1XPB, a subunit of TFIIH, is a target of the natural product triptolide by Denis V. Titov and othersxpb-a-subunit-of-tfiih-is-a-target-of-the-natural-product-triptolide-by-denis-v-titov-and-others2026-10-202026-10-20
1Dynamics and Memory of Heterochromatin in Living Cells by Nathaniel A. Hathaway and othersdynamics-and-memory-of-heterochromatin-in-living-cells-by-nathaniel-a-hathaway-and-others2026-10-202026-10-20
1RNAi-mediated targeting of heterochromatin by the RITS complex by André Verdel and othersrnai-mediated-targeting-of-heterochromatin-by-the-rits-complex-by-andre-verdel-and-others2026-10-202026-10-20
1Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi by Thomas A. Volpe and othersregulation-of-heterochromatic-silencing-and-histone-h3-lysine-9-methylation-by-rnai-by-thomas-a-volpe-and-others2026-10-202026-10-20
1KAP1 controls endogenous retroviruses in embryonic stem cells by Helen M. Rowe and otherskap1-controls-endogenous-retroviruses-in-embryonic-stem-cells-by-helen-m-rowe-and-others2026-10-202026-10-20
1In Vivo Imaging of oskar mRNA Transport Reveals the Mechanism of Posterior Localization by Vitaly L. Zimyanin and othersin-vivo-imaging-of-oskar-mrna-transport-reveals-the-mechanism-of-posterior-localization-by-vitaly-l-zimyanin-and-others2026-10-202026-10-20

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Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Video 1.
Intro to OurBigBook
. Source.
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
    Video 2.
    OurBigBook Web topics demo
    . Source.
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact
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