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1Live imaging of endogenous RNA reveals a diffusion and entrapment mechanism for nanos mRNA localization in Drosophila by Kevin M. Forrest and Elizabeth R. Gavislive-imaging-of-endogenous-rna-reveals-a-diffusion-and-entrapment-mechanism-for-nanos-mrna-localization-in-drosophila-by-kevin-m-forrest-and-elizabeth-r-gavis2026-10-202026-10-20
1Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1 by Stefan Hüttelmaier and othersspatial-regulation-of-beta-actin-translation-by-src-dependent-phosphorylation-of-zbp1-by-stefan-huttelmaier-and-others2026-10-202026-10-20
1Translational control through differential ribosome pausing during amino acid limitation in mammalian cells by Alicia M. Darnell and otherstranslational-control-through-differential-ribosome-pausing-during-amino-acid-limitation-in-mammalian-cells-by-alicia-m-darnell-and-others2026-10-202026-10-20
1Regulated translation initiation controls stress-induced gene expression in mammalian cells by Heather P. Harding and othersregulated-translation-initiation-controls-stress-induced-gene-expression-in-mammalian-cells-by-heather-p-harding-and-others2026-10-202026-10-20
1Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells by Krishna M. Vattem and Ronald C. Wekreinitiation-involving-upstream-orfs-regulates-atf4-mrna-translation-in-mammalian-cells-by-krishna-m-vattem-and-ronald-c-wek2026-10-202026-10-20
1Sestrin2 is a leucine sensor for the mTORC1 pathway by Rachel L. Wolfson and otherssestrin2-is-a-leucine-sensor-for-the-mtorc1-pathway-by-rachel-l-wolfson-and-others2026-10-202026-10-20
1Ribosome-dependent activation of stringent control by Alan Brown and othersribosome-dependent-activation-of-stringent-control-by-alan-brown-and-others2026-10-202026-10-20
1The two RNA polymerases encoded by the nuclear and the plastid compartments transcribe distinct groups of genes in tobacco plastids by P. T. Hajdukiewicz and othersthe-two-rna-polymerases-encoded-by-the-nuclear-and-the-plastid-compartments-transcribe-distinct-groups-of-genes-in-tobacco-plastids-by-p-t-hajdukiewicz-and-others2026-10-202026-10-20
1The multiple-stress responsive plastid sigma factor, SIG5, directs activation of the psbD blue light-responsive promoter (BLRP) in Arabidopsis thaliana by Akitomo Nagashima and othersthe-multiple-stress-responsive-plastid-sigma-factor-sig5-directs-activation-of-the-psbd-blue-light-responsive-promoter-blrp-in-arabidopsis-thaliana-by-akitomo-nagashima-and-others2026-10-202026-10-20
1Site-specific binding of a PPR protein defines and stabilizes 5′ and 3′ mRNA termini in chloroplasts by Jeannette Pfalz and otherssite-specific-binding-of-a-ppr-protein-defines-and-stabilizes-5′-and-3′-mrna-termini-in-chloroplasts-by-jeannette-pfalz-and-others2026-10-202026-10-20
1Light-induced psbA translation in plants is triggered by photosystem II damage via an assembly-linked autoregulatory circuit by Prakitchai Chotewutmontri and Alice Barkanlight-induced-psba-translation-in-plants-is-triggered-by-photosystem-ii-damage-via-an-assembly-linked-autoregulatory-circuit-by-prakitchai-chotewutmontri-and-alice-barkan2026-10-202026-10-20
1Sigma factor-mediated plastid retrograde signals control nuclear gene expression by Jesse D. Woodson and otherssigma-factor-mediated-plastid-retrograde-signals-control-nuclear-gene-expression-by-jesse-d-woodson-and-others2026-10-202026-10-20
1Epigenetic inheritance uncoupled from sequence-specific recruitment by Kaushik Ragunathan and othersepigenetic-inheritance-uncoupled-from-sequence-specific-recruitment-by-kaushik-ragunathan-and-others2026-10-202026-10-20
1Activation of GCN2 by the ribosomal P-stalk by Alison J. Inglis and othersactivation-of-gcn2-by-the-ribosomal-p-stalk-by-alison-j-inglis-and-others2026-10-202026-10-20
1Rapid leukocyte migration by integrin-independent flowing and squeezing by Tim Lämmermann and othersrapid-leukocyte-migration-by-integrin-independent-flowing-and-squeezing-by-tim-lammermann-and-others2026-10-202026-10-20
1A fluid-to-solid jamming transition underlies vertebrate body axis elongation by Alessandro Mongera and othersa-fluid-to-solid-jamming-transition-underlies-vertebrate-body-axis-elongation-by-alessandro-mongera-and-others2026-10-202026-10-20
1Contact inhibition of locomotion in vivo controls neural crest directional migration by Carlos Carmona-Fontaine and otherscontact-inhibition-of-locomotion-in-vivo-controls-neural-crest-directional-migration-by-carlos-carmona-fontaine-and-others2026-10-202026-10-20
1Collective invasion in breast cancer requires a conserved basal epithelial program by Kevin J. Cheung and otherscollective-invasion-in-breast-cancer-requires-a-conserved-basal-epithelial-program-by-kevin-j-cheung-and-others2026-10-202026-10-20
1An inside-out origin for the eukaryotic cell by David A. Baum and Buzz Bauman-inside-out-origin-for-the-eukaryotic-cell-by-david-a-baum-and-buzz-baum2026-10-202026-10-20
1Isolation of an archaeon at the prokaryote-eukaryote interface by Hiroyuki Imachi and othersisolation-of-an-archaeon-at-the-prokaryote-eukaryote-interface-by-hiroyuki-imachi-and-others2026-10-202026-10-20

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Pinned article: Introduction to the OurBigBook Project

Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Video 1.
Intro to OurBigBook
. Source.
We have two killer features:
  1. topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculus
    Articles of different users are sorted by upvote within each article page. This feature is a bit like:
    • a Wikipedia where each user can have their own version of each article
    • a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
    This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.
    Figure 1.
    Screenshot of the "Derivative" topic page
    . View it live at: ourbigbook.com/go/topic/derivative
    Video 2.
    OurBigBook Web topics demo
    . Source.
  2. local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:
    This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
    Figure 2.
    You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website
    .
    Figure 3.
    Visual Studio Code extension installation
    .
    Figure 4.
    Visual Studio Code extension tree navigation
    .
    Figure 5.
    Web editor
    . You can also edit articles on the Web editor without installing anything locally.
    Video 3.
    Edit locally and publish demo
    . Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension.
    Video 4.
    OurBigBook Visual Studio Code extension editing and navigation demo
    . Source.
  3. https://raw.githubusercontent.com/ourbigbook/ourbigbook-media/master/feature/x/hilbert-space-arrow.png
  4. Infinitely deep tables of contents:
    Figure 6.
    Dynamic article tree with infinitely deep table of contents
    .
    Descendant pages can also show up as toplevel e.g.: ourbigbook.com/cirosantilli/chordate-subclade
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact
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