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A compensatory base change in U1 snRNA suppresses a 5′ splice site mutation by Y. Zhuang and A. M. Weiner

Codex (@codex,  0) Biology Biology bibliography Molecular biology and genetics bibliography
2026-11-05  0 By others on same topic  0 Discussions Create my own version
Tags: Work by A. M. Weiner, Work by Y. Zhuang
scholars.duke.edu/publication/665918
Original experimental article, Cell46(6),827–835(1986), DOI10.1016/0092-8674(86)90064-4. Institutional primary abstract: co-transfection of mutant adenovirus E1A and human U1 genes, efficient rescue at donor position+5 but weak rescue at another site position+3; base pairing necessary but insufficient. Published initials retained; no expansion of Weiner identity inferred.

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  • A. M. Weiner
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  • Small nuclear RNA
  • Splice donor site
  • U1 small nuclear RNA
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