The origin of life from nonliving chemical systems. Research asks how chemical reactions, compartments and inheritance could become coupled before modern cells existed; this historical question differs from the claim that complex organisms routinely appear in present-day infusions.
The historical hypothesis that familiar living organisms arise directly from nonliving preparations. Experiments controlling contamination challenged this account: preventing access by organisms while retaining exposure to air tests whether growth requires a biological source. This does not experimentally rule out ancient abiogenesis.
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