Bmi1 is a component of a Polycomb repressive complex involved in chromatin-associated gene regulation. Its roles include regulation of developmental and proliferative programmes. Use of Bmi1 expression as a lineage marker is distinct from demonstrating its biochemical function or a uniquely defined stem-cell biological population. Interpretation therefore requires both the molecular context and the labelling strategy used in a particular experiment. [ref]
NCBI Gene by the National Library of Medicine. Homo sapiens, BMI1 record, Summary and linked functional evidence
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