If any true elementary hypothesis is rejected by a closed testing procedure, then the intersection of all true null hypotheses must also be rejected. Its local test has level , so the familywise error rate is at most under arbitrary dependence.
Past exam of the mathematics course of the University of Cambridge 2023 iii Paper 205 2 Solution 2026-09-28
The familywise error rate isThe Bonferroni correction rejects when . Since a valid p-value is super-uniform under its null, the union bound givesNo independence assumption is needed.
For the closed testing procedure, form the intersection hypothesis for every nonempty and choose a level- local test for each . Reject exactly when every with is rejected by its local test. If any true is rejected, then the intersection of all true nulls is rejected. Since its local test has significance level ,This is the closed-testing control of the familywise error rate.
Procedure (B) is the Weighted Holm step-down procedure. Let be the first rank in the ordering whose hypothesis is a true null, and put . If any true null is rejected, the procedure reaches step andbecause every true null remains among ranks . Henceand another union bound gives FWER at most .
At step , procedure (B) divides by the total weight still under consideration, which is no larger than . Its critical values therefore increase as hypotheses are rejected. Moreover, if procedure (A) would reject a hypothesis, every earlier ordered also passes the initial threshold, so procedure (B) reaches and rejects it. Thus (B) contains every rejection of (A) and can make strictly more rejections while retaining the same strong FWER control.