A complete-case analysis uses only observations for which every variable required by the analysis is observed. It can be biased when completeness selects observations according to their outcomes or other relevant variables.
Let indicate observation of a regression response , with fully observed predictors . If and on the target support, the observed conditional density equals the full conditional density. Thus a correctly specified regression model can be fitted to observed responses under conditional missing at random. This does not justify the unadjusted complete-case mean when observation rates and outcome means both vary with , nor does it imply missing completely at random.

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