For mass eigenstates , unequal forward and reverse flavour transition probabilities occur when . They are proportional to and . This diagnostic is invariant under rephasing the two flavour eigenstates.
If semileptonic decay tags the decaying flavour, wrong-sign decays require neutral meson mixing. With no direct CP violation and no wrong-sign direct decay amplitudes, their rate asymmetry is . The common time dependence cancels; contaminating direct amplitudes invalidate that isolation.

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