An endergonic reaction has positive molar reaction change in Gibbs free energy under the specified conditions. Sustained net forward conversion needs a driving process, such as energy coupling. See OpenStax Biology 2e, 6.2: endergonic reactions.
Articles by others on the same topic
An endergonic reaction is a type of chemical reaction that requires an input of energy to proceed. In these reactions, the free energy of the products is greater than the free energy of the reactants, which means that the overall change in free energy (ΔG) is positive. This characteristic indicates that the reaction is not spontaneous; it won't occur without an external source of energy. Endergonic reactions are common in biological systems.