H3K9 dimethylation Created 2026-10-20 Updated 2026-11-05
H3K9 dimethylation is addition of two methyl groups to lysine 9 of histone H3, conventionally abbreviated H3K9me2. It is associated with repressive chromatin in several systems, including extensive domains in plants. Its distribution differs from the mono- and trimethylated states of the same residue. In Arabidopsis thaliana, joint changes in this mark and non-CG DNA methylation alter recombination near centromeres, linking chromatin state to inherited variation. [ref]