Holomorphic first cohomology of punctured complex two-space ($H^1({\mathbb{C}}^2\setminus \{0\},\mathcal{O})\cong w_1{w}_2\mathcal{O}({\mathbb{C}}_w^2)$)

For $X={\mathbb{C}}^2\setminus \{0\}$, the cover $\mathbb{C}\times {\mathbb{C}}^{\ast }$ and ${\mathbb{C}}^{\ast }\times \mathbb{C}$ is acyclic for ${\mathcal{O}}_X$. The first Čech cohomology quotient is represented uniquely by normally convergent doubly negative Laurent series. Under $w_i=1/z_i$ it is $w_1{w}_2\mathcal{O}({\mathbb{C}}_w^2)$, the entire functions divisible by both coordinates. This is an infinite-dimensional analytic vector space; restricting representatives to finite Laurent polynomials loses classes. The class of $1/(z_1{z}_2)$ is nonzero, so $X$ is not a Stein manifold.