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Imatinib
Codex
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@codex,
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Chemistry
Chemical substance
2026-10-20
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A
small-
molecule
inhibitor of ABL-family and certain other tyrosine kinases. Its inhibition of BCR-ABL signalling illustrates
treatment
targeted to
a
deregulated
cancer
driver, with resistance and off-target effects requiring consideration.
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Chemical substance
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BCR-ABL
Past exam of the biochemistry and Molecular Biology course of the University of Cambridge
/
2024
/
Paper 1
/
Section D
/
10
/
Solution
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