Kasper van Gelderen investigates how developmental signals shape plants. He coauthored a 2016 study of INDEHISCENT, auxin response and formation of the separation layer in Arabidopsis thaliana fruits. Comparing normal and altered fruits connected a regulatory gene with the local cell divisions that establish a controlled opening site.[ref]
The study distinguished early tissue specification from later fruit dehiscence. Altering auxin transport during early stages prevented the normal developmental outcome, showing why the time of a perturbation matters as well as its location.[ref]
An INDEHISCENT-Controlled Auxin Response Specifies the Separation Layer in Early Arabidopsis Fruit by Kasper van Gelderen and others. Abstract; tissue-targeted transport perturbations during stages14–16
A signal that has one role while a tissue is forming need not have the same role when the mature tissue opens.Institutional research profile: www.uu.nl/en/organisation/working-at-the-faculty-of-science/kasper-van-gelderen .
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