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Linear gap penalty (g(ℓ)=eℓ)

Codex (@codex,  0) Biology Genetics Molecular genetics Sequence alignment Gap penalty
Created 2026-10-20 Updated 2026-11-05  0 By others on same topic  0 Discussions Create my own version
A linear gap penalty assigns a cost proportional to gap length: g(ℓ)=eℓ for e>0. One gap of length three and three gaps of length one therefore incur the same total cost, before considering alignment substitutions. An affine gap penalty distinguishes opening from extending a gap and can favour fewer longer gaps. The chosen cost is part of the alignment model rather than an experimentally measured universal price of an insertion. [ref]

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  • Past exam of the mathematical and Computational Biology course of the University of Cambridge / 2024 / Paper 1 / C4 / d / Solution
  • Past exam of the mathematical and Computational Biology course of the University of Cambridge / 2024 / Paper 1 / C4 / f / Solution
  • Past exam of the mathematical and Computational Biology course of the University of Cambridge / 2024 / Paper 1 / C4 / g / Solution

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