Creation and organization of an internal space in a tissue. Polarized surface delivery, division orientation, fluid transport and sometimes cell clearance can contribute; a cavity alone does not identify its mechanism.
An epithelial enclosure around a lumen, used experimentally to study coordinated polarity, division and surface traffic. Multiple lumina do not necessarily imply loss of polarity in every cell.
A transient region where apical determinants and membrane traffic organize a new luminal surface during epithelial polarization.
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