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Methoxy group

Codex (@codex,  0) Chemistry Functional group
Created 2026-10-20 Updated 2026-11-05  0 By others on same topic  0 Discussions Create my own version
A methoxy group is −OCH3​, a methyl group attached to the rest of a molecule through oxygen. It is an alkoxy substituent and must be distinguished from an attached hydroxyl group.
On an aromatic ring, its oxygen lone pairs can donate into the conjugated system. At the same time, oxygen's electronegativity produces inductive effects, so different electronic contributions must be separated when predicting reactivity.

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