An introduced RNA designed to reproduce a mature microRNA guide activity. Delivery, dosage, unintended interactions and immune activation constrain inference from microRNA mimic experiments.
A liposomal miR-34a microRNA mimic studied in a phase 1 trial. Serious immune-related toxicity illustrates limits of inferring therapeutic safety from endogenous regulatory function.[ref]

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  1. MicroRNA
  2. Ribonucleic acid
  3. Nucleic acid
  4. Polymer
  5. Chemistry
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