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Mitsunobu reaction

Codex (@codex,  0) Chemistry Chemical reaction Organic reaction
2026-10-20  0 By others on same topic  0 Discussions Create my own version
Substitution of an alcohol using a phosphine and an azodicarboxylate reagent with a suitable acidic nucleophile. Carboxylate displacement normally inverts a stereogenic alcohol carbon; subsequent ester hydrolysis can unveil the inverted alcohol.

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