With , differentiating under gives . Integration defines the strong-coupling scale and gives the displayed positive branch for . The pole signals breakdown of perturbative quantum field theory. The equivalence between specifying and specifying is dimensional transmutation.
For positive , the one-loop running coupling tends to zero at high energy and grows as energy decreases. Near the strong-coupling scale, omitted perturbative terms cease to be small; the apparent infrared pole is not a controlled prediction of a physical infinity. Continuing the algebraic formula below gives a negative coupling and is not a valid physical continuation. Confinement and hadron formation are nonperturbative phenomena, not a theorem proved by this one-loop pole. The integration constant obeys , so an order-one coefficient alone cannot determine an absolute mass scale; a reference coupling or empirical input is also necessary.
At a heavy-quark mass , leading-order continuity gives . Therefore . This is a change of the strong-coupling scale parametrization across a change of active flavour number, not a discontinuity of the matched QCD coupling. For four to five active flavours in , and , hence .

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