Outcome standardization 2026-10-14
Outcome standardization averages fitted conditional outcome risks over a specified target population's pretreatment covariate distribution. The same target distribution is used for each treatment strategy. Under conditional exchangeability, the positivity assumption and consistency, this average identifies the target mean of the corresponding potential outcomes. For a target consisting of treated subjects, average over their covariate distribution. A conditional odds ratio cannot generally be applied directly to an aggregate mean risk: the nonlinear odds-to-probability conversion must be performed before averaging. Outcome standardization supplies that individual-risk calculation.
Past exam of the mathematics course of the University of Cambridge 2010 iii Paper 34 1 f Solution Created 2026-10-03 Updated 2026-10-14
As a rough rare-event calculation, divide the observed elective-group event count by the reported adjusted odds ratio:For a homogeneous illustrative risk, the exact odds conversion starts from and givesThe corresponding baseline risk is about , compared with in the observed reference group, roughly seven times lower. Thus taking the adjusted result literally implies exceptionally low background risk among the elective patients.
This is a diagnostic approximation, not an identified mean of potential outcomes obtainable from the aggregate table. A conditional odds ratio cannot generally be inverted at an aggregate mean: individual background risks are needed for outcome standardization. Interpreting the calculation causally also requires conditional exchangeability, the positivity assumption and a correctly specified outcome model. At very small risks the rare-event approximation makes the estimate of roughly three events useful for checking the plausibility of the adjustment.