Suppose and that the interiors of and cover . The Mayer-Vietoris theorem gives the long exact sequence in homologywhere all four displayed maps except the connecting homomorphism are induced by the relevant inclusion maps.
To prove it, let be the chain complex generated by those singular simplices whose images lie wholly in or wholly in . The sequenceis a short exact sequence of chain complexes. Repeated barycentric subdivision makes every singular simplex small enough to lie in or , and the subdivision operator is chain homotopic to the identity. The inclusion therefore induces an isomorphism on every homology group. The long exact homology sequence of a short exact sequence of chain complexes now gives the displayed sequence. Explicitly, if an -cycle with and , then lies in and represents the connecting class .
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