- Instrument relevance: the conditional law of changes with .
- Instrumental-variable independence: is independent of the joint collection of potential treatments and outcomes, such as .
- The exclusion restriction: , so can affect only through .
- Consistency of potential outcomes and no interference in causal inference connect the potential variables to the observations.
In the graph, has open noncausal paths to that do not pass through , includingEquivalently, these paths remain after deleting the causal edge . Thus is associated with potential outcomes through the latent variables and , violating instrumental-variable independence; it is not a valid marginal instrument.
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