Capacity to generate the principal embryonic cell lineages under suitable conditions. Expression of one stem-cell marker alone does not establish this capacity.
A pluripotent state associated with later epiblast and readiness to respond to lineage-specifying signals. It is experimentally and molecularly distinct from naive pluripotency.
A transitional pluripotent state in which naive circuitry has been dismantled while competence for later lineage induction is being acquired. This is a state transition, not an additional germ layer.
A pluripotent state associated with the preimplantation mouse epiblast and a characteristic regulatory network. Naive cells differ from the postimplantation epiblast in signalling requirements, chromatin state and responsiveness to differentiation cues.

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