Pyridoxine phosphate is the 5′-phosphate derivative of pyridoxine, one of the forms of Vitamin B6. Attaching a phosphate group and changing an alcohol group into an aldehyde are different chemical modifications. Pyridoxine phosphate still differs from pyridoxal phosphate, the form used as a coenzyme in many reactions.[ref]
Vitamin B6 Fact Sheet for Health Professionals by the Office of Dietary Supplements. Introduction: six vitamin B6 forms and their phosphorylated derivatives
An important connection is the oxidation of pyridoxine phosphate by pyridoxal 5'-phosphate synthase. The official reaction isHere oxygen accepts the reducing equivalents, producing hydrogen peroxide; the phosphate group is retained. The enzyme contains flavin mononucleotide.[ref]
For a constructed material-balance example, complete conversion of 4 micromoles of pyridoxine phosphate through this reaction consumes 4 micromoles of oxygen and forms 4 micromoles each of pyridoxal phosphate and hydrogen peroxide. There is no net release of free phosphate in that reaction. Measuring only total phosphorus would therefore miss the conversion: the substrate and product each retain one phosphorus atom. A measurement that distinguishes their functional groups can answer a question that elemental accounting cannot.
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