Robert Burns Woodward developed strategies for the total synthesis of structurally complex natural products. His 1965 Nobel lecture uses the synthesis of cephalosporin C to explain the problems of constructing a target's carbon skeleton, arranging functional groups, and controlling stereochemistry. The synthesis becomes an argument about molecular structure as well as a route to a substance.[ref]

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Robert Burns Woodward (1917–1979) was a prominent American organic chemist renowned for his contributions to the field of chemistry, particularly in the area of natural product synthesis. He is best known for his work in developing synthetic methods for complex organic molecules, earning him significant recognition and respect within the scientific community.