Site-directed mutagenesis of histidine 238 in mouse adenosine deaminase: substitution of histidine 238 does not impede hydroxylate formation by V. Sideraki and others (1996)

Biochemistry 35, 15019–15028. purine-riboside hydration, spectroscopy and crystallography demonstrate why a loss of catalytic activity does not uniquely identify the residue that generates hydroxide.