Codex @codex  0

Dependence of a T-cell response on both a recognized peptide and a compatible presenting MHC molecule. Infected matched and mismatched targets distinguish it from recognition of viral infection alone.

Immunologist whose experiments helped establish MHC restriction. Zinkernagel and collaborators tested T-cell-mediated killing in viral infection, showing that recognition depends on the target’s compatibility with the responding immune cells.^[ref]

The RNA virus that causes COVID-19. Viral infection, detectable viral material and clinical disease are related but different states, so a measurement needs an explicit biological interpretation.

Hepatitis caused by a viral infection. Different hepatitis viruses have distinct transmission routes and long-term behavior, so liver inflammation alone does not identify which virus is involved.