Cancer is natural selection gone wrong by 
Ciro Santilli 35 Updated 2025-01-10 +Created 1970-01-01
Ciro Santilli 35 Updated 2025-01-10 +Created 1970-01-01A cool thought about cancer expressed at Power, Sex, Suicide by Nick Lane (2006) is that cancer it is the direct product of natural selection gone wrong!
Cancer cells are obviously selected against anti-cancer mechanism, which when they manage to evade, they reproduce uncontrollably, gaining more and more momentum.
Sequence alignment is trying to match a DNA or amino acid sequence, even though the sequences might not be exactly the same, otherwise it would be a straight up string-search algorithm.
This is fundamental in bioinformatics for two reasons:
- when you sequence the DNA of a new species, you can guess what each protein does by comparing it with similar proteins in other species that you have already studied
- when doing DNA sequencing, and specially short-read DNA sequencing, you generally need to align the reads to reference genomes to know where you are inside the entire genome, and then be able to spot mutations, notably single-nucleotide polymorphisms
Small microscopic visible particles move randomly around in water.
If water were continuous, this shouldn't happen. Therefore this serves as one important evidence of atomic theory.
The amount it moves also quantitatively matches with the expected properties of water and the floating particles, was was settled in 1905 by Einstein at: investigations on the theory of the Brownian movement by Einstein (1905).
This suggestion that Brownian motion comes from the movement of atoms had been made much before Einstein however, and passed tortuous discussions. Subtle is the Lord by Abraham Pais (1982) page 93 explains it well. There had already been infinite discussion on possible causes of those movements besides atomic theory, and many ideas were rejected as incompatible with observations:The first suggestions of atomic theory were from the 1860s.
Further investigations eliminated such causes as temperature gradients, mechanical disturbances, capillary actions, irradiation of the liquid (as long as the resulting temperature increase can be neglected), and the presence of convection currents within the liquid.
Tiny uniform plastic beads called "microbeads" are the preferred 2019 modern method of doing this: en.wikipedia.org/wiki/Microbead
Original well known observation in 1827 by Brown, with further experiments and interpretation in 1908 by Jean Baptiste Perrin. Possible precursor observation in 1785 by Jan Ingenhousz, not sure why he wasn't credited better.
Taboola is a clickbait trained neural network. Which happens to have been written by Adolf Hitler.
- www.youtube.com/channel/UCM2YmsRUeIbRkqjgNm0eTGQ Journeyman Pictures. Basically a VICE-like, focused on fucked up things happening in poor countries or regions.
- Mediocre Amateur
- 1958: myoglobin structure resolution (1958). The first protein to be resolved.
- 1965: lysozyme structure resolution (1965). The second protein to be resolved.
How to use a single source multiple times in a Wikipedia article? by Ciro Santilli 35 Updated 2025-01-10 +Created 1970-01-01
Ciro Santilli 35 Updated 2025-01-10 +Created 1970-01-01en.wikipedia.org/wiki/Help:Footnotes#Footnotes:_using_a_source_more_than_once gives the following method:
Definition, anywhere on article, likely ideally as the first usage:
<ref name="myname">{{cite web ...}}</ref>And then you can use it later on as:which automatically expands the exact same thing, or using the shortcut:
<ref name="myname" />{{r|myname}}To cite multiple pages of a book: en.wikipedia.org/wiki/Wikipedia:Citing_sources#Citing_multiple_pages_of_the_same_source, the best method is to define and use the reference without adding the Do not set the page in or for multiple pages:
p or location in cite as:<ref name="googleStory">{{cite book |title=The Google Story}}</ref>{{rp|p=123}}cite, otherwise it shows up on the references. Instead we use the {{rp}} template. And then use the reference with the {{r}} template as:{{r|googleStory|p=456}}{{r|googleStory|pp=123, 156-158}} Unlisted articles are being shown, click here to show only listed articles.