ROMK (also known as Kir4.1) is a protein that is encoded by the KCNJ10 gene in humans. It is a member of the inward rectifier potassium (Kir) channel family, which plays a crucial role in maintaining the resting membrane potential of cells and regulating potassium ion flow across cell membranes. ROMK is particularly important in the kidney, where it is involved in the reabsorption of potassium ions in the renal tubules.

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