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COPII-coated vesicle formation reconstituted with purified coat proteins and chemically defined liposomes by Ken Matsuoka and others by
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Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination by Yasuko Murakami and others by
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Primary source: www.nature.com/articles/360597a0
Cited material: Immunodepletion and purified 26S-proteasome degradation assays, pp. 597–599.
Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae by Miki Tsukada and Yoshinori Ohsumi by
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Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing by Dirk Remus and others by
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Driving the cell cycle with a minimal CDK control network by Damien Coudreuse and Paul Nurse by
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Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion by Akira Orimo and others by
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A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors by Jeffrey Wyckoff and others by
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Tumour exosome integrins determine organotropic metastasis by Ayuko Hoshino and others by
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Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion by Cristovão M. Sousa and others by
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Published erratum: doi.org/10.1038/nature19851. Consult the corrected article.
Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival by Berna C. Özdemir and others by
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Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1 by Frank Uhlmann and others by
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An ECT2-centralspindlin complex regulates the localization and function of RhoA by Özlem Yüce and others by
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Aurora B-mediated abscission checkpoint protects against tetraploidization by Patrick Steigemann and others by
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Regulated eukaryotic DNA replication origin firing with purified proteins by Joseph T. P. Yeeles and others by
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Independent and stochastic action of DNA polymerases in the replisome by James E. Graham and others by
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Oncogenic signaling pathways in The Cancer Genome Atlas by Francisco Sanchez-Vega and others by
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Mutational heterogeneity in cancer and the search for new cancer-associated genes by Michael S. Lawrence and others by
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Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR by Anirudh Prahallad and others by
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Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis by Jing Yang and others by
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Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.Figure 3. Visual Studio Code extension installation.Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. - Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact





