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Regulation of Golgi structure and secretion by receptor-induced G protein βγ complex translocation by Deepak Kumar Saini and others by
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Proceedings of the National Academy of Sciences 107, 11417–11422 (2010). doi.org/10.1073/pnas.1003042107
Crystal structures of a multidrug transporter reveal a functionally rotating mechanism by Satoshi Murakami and others by
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Nature 443, 173–179 (2006). doi.org/10.1038/nature05076
Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop by Thomas Eicher and others by
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Proceedings of the National Academy of Sciences 109, 5687–5692 (2012). doi.org/10.1073/pnas.1114944109
Homeoviscous adaptation—a homeostatic process that regulates the viscosity of membrane lipids in Escherichia coli by Michael Sinensky by
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Proceedings of the National Academy of Sciences 71, 522–525 (1974). doi.org/10.1073/pnas.71.2.522
Separation of liquid phases in giant vesicles of ternary mixtures of phospholipids and cholesterol by Sarah L. Veatch and Sarah L. Keller by
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Biophysical Journal 85, 3074–3083 (2003). doi.org/10.1016/S0006-3495(03)74726-2
Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape by Joseph H. Lorent and others by
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Conformational biosensors reveal GPCR signalling from endosomes by Roshanak Irannejad and others by
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Nature 495, 534–538 (2013). doi.org/10.1038/nature12000
Deciphering the splicing code by Yoseph Barash and others by
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Original research by Yoseph Barash and colleagues.
An RNA map predicting Nova-dependent splicing regulation by Jernej Ule and others by
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Original research by Jernej Ule and colleagues.
N6-methyladenosine-dependent RNA structural switches regulate RNA–protein interactions by Nian Liu and others by
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Thiol-linked alkylation of RNA to assess expression dynamics by Veronika A. Herzog and others by
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Original research by Veronika A. Herzog and colleagues.
Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation by Huilin Huang and others by
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Original research by Huilin Huang and colleagues.
Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers by Leighton J. Core and others by
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Original research by Leighton J. Core and colleagues.
The human initiator is a distinct and abundant element that is precisely positioned in focused core promoters by Long Vo ngoc and others by
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Original research by Long Vo ngoc and colleagues.
XPB, a subunit of TFIIH, is a target of the natural product triptolide by Denis V. Titov and others by
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Original research by Denis V. Titov and colleagues.
Dynamics and Memory of Heterochromatin in Living Cells by Nathaniel A. Hathaway and others by
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Original research by Nathaniel A. Hathaway and colleagues.
RNAi-mediated targeting of heterochromatin by the RITS complex by André Verdel and others by
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Original research by André Verdel and colleagues.
Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi by Thomas A. Volpe and others by
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Original research by Thomas A. Volpe and colleagues.
KAP1 controls endogenous retroviruses in embryonic stem cells by Helen M. Rowe and others by
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Original research by Helen M. Rowe and colleagues.
In Vivo Imaging of oskar mRNA Transport Reveals the Mechanism of Posterior Localization by Vitaly L. Zimyanin and others by
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Pinned article: Introduction to the OurBigBook Project
Welcome to the OurBigBook Project! Our goal is to create the perfect publishing platform for STEM subjects, and get university-level students to write the best free STEM tutorials ever.
Everyone is welcome to create an account and play with the site: ourbigbook.com/go/register. We belive that students themselves can write amazing tutorials, but teachers are welcome too. You can write about anything you want, it doesn't have to be STEM or even educational. Silly test content is very welcome and you won't be penalized in any way. Just keep it legal!
Intro to OurBigBook
. Source. We have two killer features:
- topics: topics group articles by different users with the same title, e.g. here is the topic for the "Fundamental Theorem of Calculus" ourbigbook.com/go/topic/fundamental-theorem-of-calculusArticles of different users are sorted by upvote within each article page. This feature is a bit like:
- a Wikipedia where each user can have their own version of each article
- a Q&A website like Stack Overflow, where multiple people can give their views on a given topic, and the best ones are sorted by upvote. Except you don't need to wait for someone to ask first, and any topic goes, no matter how narrow or broad
This feature makes it possible for readers to find better explanations of any topic created by other writers. And it allows writers to create an explanation in a place that readers might actually find it.Figure 1. Screenshot of the "Derivative" topic page. View it live at: ourbigbook.com/go/topic/derivativeVideo 2. OurBigBook Web topics demo. Source. - local editing: you can store all your personal knowledge base content locally in a plaintext markup format that can be edited locally and published either:This way you can be sure that even if OurBigBook.com were to go down one day (which we have no plans to do as it is quite cheap to host!), your content will still be perfectly readable as a static site.
- to OurBigBook.com to get awesome multi-user features like topics and likes
- as HTML files to a static website, which you can host yourself for free on many external providers like GitHub Pages, and remain in full control
Figure 2. You can publish local OurBigBook lightweight markup files to either OurBigBook.com or as a static website.Figure 3. Visual Studio Code extension installation.Figure 5. . You can also edit articles on the Web editor without installing anything locally. Video 3. Edit locally and publish demo. Source. This shows editing OurBigBook Markup and publishing it using the Visual Studio Code extension. - Infinitely deep tables of contents:
All our software is open source and hosted at: github.com/ourbigbook/ourbigbook
Further documentation can be found at: docs.ourbigbook.com
Feel free to reach our to us for any help or suggestions: docs.ourbigbook.com/#contact





