 Chemotactic instability on a rectangular domain

For cell diffusion, self-produced chemotactic agent and logistic proliferation, Neumann cosine modes reduce linear stability of the uniform state to a two-by-two matrix indexed by $s={\pi }^2(n^2/L_1^2+m^2/L_2^2)$. Its trace is negative and its determinant is $D(s)=\alpha s^2+(1+\alpha \kappa -\beta \kappa \eta )s+\kappa$. Chemotaxis can destabilize a mode precisely when $D(s)<0$, despite stability of the spatially uniform reaction system.