IP3 production by phospholipase C
ID: ip3-production-by-phospholipase-c
Phospholipase C catalyzes hydrolysis of membrane PIP2, producing soluble IP3 and membrane-associated diacylglycerol. This consumes a phospholipid substrate, rather than manufacturing calcium. G protein-regulated and receptor tyrosine kinase-regulated forms of PLC provide different routes to this reaction.[ref]
Pathways of Intracellular Signal Transduction. Phospholipids and Ca2+, Figures 13.24–13.25: PIP2 hydrolysis and distinct PLC activation routes
New to topics? Read the docs here!