Solution

ID: past-exam-of-the-mathematical-and-computational-biology-course-of-the-university-of-cambridge/2025/paper-1/3/b/solution

Using divisor , the covariance matrix is
For example, the first variance is , and the first-second covariance is . If “sample covariance matrix” means the unbiased convention, use divisor instead: . This multiplies every eigenvalue by and leaves all principal component loadings and explained-variance fractions unchanged.

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