A coordinate transformation considered solely asa relabeling of events has no independent observable outcome: changing labels changes neither a detector record nor a clock comparison. But the Lorentz transformations also express substantive relations between operationally realized inertial coordinates. With clocks and rulers specified, their velocity-dependent time dilation, length relations and velocity composition make testable claims about how material systems and electromagnetic signals behave.
The distinction matters for synchronization. One-way coordinate light speed depends on how distant clocks are synchronized; a conventional alteration changes the displayed transformation law while leaving two-way timing observations unchanged. It would therefore be incorrect to regard every coefficient in an unspecified coordinate formulaasa separately measurable physical fact. Testable content comes from the transformation together with the protocol and dynamical behavior of the systems implementing the coordinates.
Thus the answer is qualified: transformations as passive mathematical changes are not experiments, while Lorentzian relations among specified measuring procedures have substantial empirical consequences. Separating these roles avoids both treating coordinate convention asa measured force and declaring the entire relativistic structure immune to evidence.