A spirometer is an instrument for measuring gas volume changes associated with breathing. Its output supports spirometry. A displacement design follows the movement of a gas-containing chamber; a flow-measuring design records volumetric flow rate and integrates it. In a pneumotachograph, a measured pressure difference across a flow-resistive element supplies the signal used to estimate volumetric flow rate.
For an ideal piston with cross-sectional area and displacement , the transferred volume is . For a flow-measuring instrument,These are different measurement chains for the same volume change. The 2019 primary technical statement explicitly discusses volume and flow instruments and their quality assurance.[ref]
Standardization of Spirometry 2019 Update by Brian L. Graham and others. Equipment and Device Quality Assurance
An original error model makes integration drift visible. If a flow sensor reports , with constant gain and zero offset , its integrated result isAn offset of contributes 0.020 L during one second but 0.20 L during ten seconds. It can therefore change a long-expiration total more than an early timed volume, even though the flow offset is constant. A gain error instead scales both in proportion when no offset is present.
Spirometer calibration verification uses a known gas transfer to test the assembled measurement chain. The 2019 statement specifies at least daily verification with a 3-L syringe at several flows and a measured-volume accuracy requirement of ±3%.[ref]
Standardization of Spirometry 2019 Update by Brian L. Graham and others. Calibration and Quality Control: 3-L syringe, multiple flow rates and accuracy requirement
For a stipulated ideal 3.000 L transfer, a report of 3.090 L differs by 3%; identical total volumes at different transfer speeds can also expose a flow-dependent response. New to topics? Read the docs here!