file 5.36 however does use it to display file type as explained at: stackoverflow.com/questions/34519521/why-does-gcc-create-a-shared-object-instead-of-an-executable-binary-according-to/55704865#55704865Contains the genes: e. Coli K-12 MG1655 gene thrL, e. Coli K-12 MG1655 gene thrA, e. Coli K-12 MG1655 gene thrB and e. Coli K-12 MG1655 gene thrC, all of which have directly linked functionality.
We can find it by searching for the species in the BioCyc promoter database. This leads to: biocyc.org/group?id=:ALL-PROMOTERS&orgid=ECOLI.
That page lists several components of the promoter, which we should try to understand!
Some of the transcription factors are proteins:
After the first gene in the codon, thrL, there is a rho-independent termination. By comparing:we understand that the presence of threonine or isoleucine variants, L-threonyl and L-isoleucyl, makes the rho-independent termination become more efficient, so the control loop is quite direct! Not sure why it cares about isoleucine as well though.
Includes:
- amphibians
- amniotes, which includes:
- sauropsida: reptiles and birds, which really are reptiles
- mammals
The exact relationships between those clades is not very clear as there's a bunch of extinct species in the middle we are not sure exactly where they go exactly, some hypothesis are listed at: en.wikipedia.org/w/index.php?title=Tetrapod&oldid=1053601110#Temnospondyl_hypothesis_(TH)
Happening multiple times a day on Ubuntu 22.04 for Chromium, even though I turn computer on and off daily, unbearable:
- askubuntu.com/questions/1412575/pending-update-of-snap-store
- askubuntu.com/questions/1412140/pending-update-of-firefox-snap-close-the-app-to-avoid-disruptions
- forum.snapcraft.io/t/how-to-disable-snapd-update-notifications-permanently/31117 Settings > Notifications > Snapd User Session Agent
- www.reddit.com/r/Ubuntu/comments/v1s919/disable_pending_update_of_snap_message_kiosk/
- forum.snapcraft.io/t/refresh-app-awareness-call-for-testing/29123
Please refer to Video "Linus Torvalds saying "Nvidia Fuck You" (2012)".
Does not happen every time, only some times. Can't figure out why. Usually happens when has suspended for a longer time.
bugs.launchpad.net/ubuntu/+source/nvidia-graphics-drivers-470/+bug/1946303 sounds like a likely report, Nvidia driver version 470, but can't find those error messages anywhere. The last line of:once was:which is when sleep starts.
journalctl -o short-precise -k -b -1PM: suspend entry (deep)This suggests that it is not a video bug then, seems that it is not waking up at all? Gotta try to SSH into it. OK. I did SSH into it, and that was fine, so it is just the video that won't start.
PM: suspend exitbugs.launchpad.net/ubuntu/+source/linux/+bug/1949977 is another possible bug, based on kernel version. I'm running 5.13, which is one of the failing versions on the report. Can't find any interesting dmesg though.
In another crash:had the following interesting lines:and there was a corresponding
journalctl -o short-precise -k -b -1nvidia-modeset: WARNING: GPU:0: Lost display notification (0:0x00000000); continuing.
[24307.640014] NVRM: GPU at PCI:0000:01:00: GPU-18af74bb-7c72-ff70-e447-87d48378ea20
[24307.640018] NVRM: Xid (PCI:0000:01:00): 79, pid=8828, GPU has fallen off the bus.
[24307.640021] NVRM: GPU 0000:01:00.0: GPU has fallen off the bus.
[24328.054022] nvidia-modeset: ERROR: GPU:0: The requested configuration of display devices (LGD (DP-4)) is not supported on this GPU.
[repeats several more times]
[24328.056767] nvidia-modeset: ERROR: GPU:0: The requested configuration of display devices (LGD (DP-4)) is not supported on this GPU.
[24328.056951] nvidia-modeset: ERROR: GPU:0: Failed to query display engine channel state: 0x0000927c:0:0:0x0000000f
[24328.056955] nvidia-modeset: ERROR: GPU:0: Failed to query display engine channel state: 0x0000927c:1:0:0x0000000f
[24328.056959] nvidia-modeset: ERROR: GPU:0: Failed to query display engine channel state: 0x0000927c:2:0:0x0000000f
[24328.056962] nvidia-modeset: ERROR: GPU:0: Failed to query display engine channel state: 0x0000927c:3:0:0x0000000f
[24328.056983] nvidia-modeset: ERROR: GPU:0: DP-4: Failed to disable DisplayPort audio stream-0
[24328.056992] nvidia-modeset: ERROR: GPU:0: Failed to query display engine channel state: 0x0000947d:0:0:0x0000000f/var/crash/_usr_sbin_gdm3.0.crash.Related "GPU has fallen off the bus": askubuntu.com/questions/868321/gpu-has-fallen-off-the-bus-nvidia
Allow us to determine with good approximation in a multi-electron atom which electron configuration have more energy. It is a bit like the Aufbau principle, but at a finer resolution.
Note that this is not trivial since there is no explicit solution to the Schrödinger equation for multi-electron atoms like there is for hydrogen.
For example, consider carbon which has electron configuration 1s2 2s2 2p2.
She's truly passionate about health research and keeping healthy, almost obsessed by it. Also she's strong willed, and energetic. Good traits for founding 23andMe.
- www.vanityfair.com/style/2014/04/sergey-brin-amanda-rosenberg-affair Fantastic painting of the people.
As www.nytimes.com/2017/11/18/style/anne-wojcicki-23andme-genetics.html puts it well:
The Wojcickis grew into Silicon Valley royalty. It’s the sort of family, Anne jokes, where “you’re only a viable fetus once you have your Ph.D.
Anne Wojcicki interview by Talks at Google (2018)
Source. She's athletic! As mentioned at: www.vanityfair.com/style/2014/04/sergey-brin-amanda-rosenberg-affair. And despite the name, and unlike Sergey, she's completely american as seen from her perfect accent!- youtu.be/pDoALM0q1LA?t=173 coding on garage while they do dishes and burritos
- youtu.be/pDoALM0q1LA?t=331 why she's obsessed with healthcare. Also mentioned at: www.vanityfair.com/style/2014/04/sergey-brin-amanda-rosenberg-affair how she was trying to save Sergei from some of his genetic predispositions
- youtu.be/pDoALM0q1LA?t=571 she really cared about 23andMe, but the public didn't as much as her. She's truly passionate about mining genetic data. Maybe she came a bit early.
- youtu.be/pDoALM0q1LA?t=1038 doc in a box workaround
www.facebook.com/watch/live/?mibextid=qC1gEa&ref=watch_permalink&v=10100156534675351 claims to have a video of Benji Wojin and his cousin Marco Troper from 2018. www.linkedin.com/posts/superintendents_marco-and-benji-wojin-love-these-kids-and-activity-7164448664772435968-siUC/ that links to it is lamenting Marco Troper 's death in 2024.
Claimed photos can be found at:All of the above are likely of the same child.
- foreign keys are capitalized:
- you must give
foreignKeywhen using aliases, otherwise it fails subtely. That would be derived automatically. - stackoverflow.com/questions/41502699/return-flat-object-from-sequelize-with-association can't auto-flatten to reuse the database's
ORDER limitandoffsetdon't work withoutsubQuery: falsewhen doing includes! It is just too buggy. Examples of this can be found e.g. under nodejs/sequelize/many_to_many_same_model.js.- stackoverflow.com/questions/34059081/how-do-i-reference-an-association-when-creating-a-row-in-sequelize-without-assum hard to not duplicate foreign keys values everywhere
- stack traces permanently broken or requiring non-obvious configs:
- does not automatically update fields on hooks: github.com/sequelize/sequelize/issues/8586#issuecomment-422877555
- cannot change columns when other columns have constraints due to the backup table?
- you have to use
.get()forattributealiased fields, why? stackoverflow.com/questions/32649218/how-do-i-select-a-column-using-an-alias/69890944#69890944 .idgets added toSELECTno matter what, breakingGROUP BYunless you do horrible workarounds:- no simple built-in mechanism for transaction retries: Sequelize transaction retries
- impossible to do subqueries in general. Docs just tell you to use literals. This in particular prevents single query deletes with join as done at nodejs/sequelize/raw/many_to_many.js:Also, you can't get query strings either: github.com/sequelize/sequelize/issues/2325
- sequelize.org/master/manual/sub-queries.html: the docs actually just tell you to use literals, lol
- stackoverflow.com/questions/45354001/nodejs-sequelize-delete-with-nested-select-query
- migrations. Generally speaking, anything but the simplest migrations are exceedingly hard to get right, as you have to go very low level when doing migrations. Syntax can be very different from regular DB operations.
- no way to do (non-raw) queries during migrations, e.g. to update fields based on other fields in a complex way?
- github.com/sequelize/cli/issues/862
- stackoverflow.com/questions/18742962/add-data-in-sequelize-migration-script
- stackoverflow.com/questions/38671483/sequelize-migration-update-model-after-updating-column-attributes
- stackoverflow.com/questions/38998397/can-i-use-sequelize-models-in-migration-scripts
- stackoverflow.com/questions/45286429/custom-query-on-sequelize-seeder
queryInterface.sequelize.modelscontains onlySequelizeMeta. Not sure why they have this limitation. - stackoverflow.com/questions/56043246/node-js-sequelize-no-primary-keys-when-migrating/56046101#56046101
- SQLite
changeColumnmigrations do on delete cascades of other tables. SQLite does not have change column statements, so they have to drop and recreate tables, but they don't temporarily remove cascades, so you lose data: stackoverflow.com/questions/62667269/sequelize-js-how-do-we-change-column-type-in-migration/70486686#70486686 - associations require full explicit index construction: stackoverflow.com/questions/39651853/how-to-create-join-table-with-foreign-keys-with-sequelize-or-sequelize-cli
- ability to iterate over a large result without blowing up memory and without using limit + offset (which is inneficient e.g. when looping over recursive queries). This is also known as cursor or streaming interfaces:E.g. the Python SQLite interface supports this just fine: stackoverflow.com/questions/29582736/python3-is-there-a-way-to-iterate-row-by-row-over-a-very-large-sqlite-table-wi
- stack overflow
- stackoverflow.com/questions/28787889/how-can-i-set-up-sequelize-js-to-stream-data-instead-of-a-promise-callback
- stackoverflow.com/questions/43964067/how-to-implement-cursor-pagination-using-sequelize
- stackoverflow.com/questions/57164242/perform-sequelize-findall-in-a-huge-array
- stackoverflow.com/questions/55191891/how-to-loop-through-result-in-sequelize generic loop
- issue tracker
- stack overflow
- empty
attributes: []breaks some nested queries: github.com/sequelize/sequelize/issues/16436 - does not expose a iteration API that supports large arrays?E.g. Python SQLite does: stackoverflow.com/questions/29582736/python3-is-there-a-way-to-iterate-row-by-row-over-a-very-large-sqlite-table-wi
To run examples on a specific database:All examples can be tested on all databases with:
./index.jsor./index.js l: SQLite./index.js p: PostgreSQL. You must manually create a database calledtmpand ensure that peer authentication works for it
cd sequelize
./testOverview of the examples:
- nodejs/sequelize/index.js: a bunch of basic examples
- nodejs/sequelize/update.js: This file is also where we are storing our expression-foo for now, e.g. how to do stuff like
col1 + col2. Such knowledge can however be used basically anywhere else however, e.g. inASorWHEREclauses, not just inUPDATE. - nodejs/sequelize/count.js: a simplified single-table count example. In practice, this will be usually done together with JOIN queries across multiple tables. Answers: stackoverflow.com/questions/22627258/how-does-group-by-works-in-sequelize/69896449#69896449
- nodejs/sequelize/date.js: automatic date typecasts
- nodejs/sequelize/like.js: LIKE
- nodejs/sequelize/camel_case.js: trying to get everything in the database camel cased, columns starting with lowercase, and tables starting with uppercase. The defaults documented on getting started documentation do uppercase foreign keys, and lowercase non-foreign keys. It's a mess.
- nodejs/sequelize/ignore_duplicates.js: ignore query on unique violation with
ignoreDuplicates: truewhich does SQLiteINSERT OR IGNORE INTOor PostgreSQLON CONFLICT DO NOTHING. Closely related Upsert versions:- Upsert
- nodejs/sequelize/upsert.js:
.upsertselects the conflict column automatically by unique columns. Both SQLite and PostgreSQL doINSERT INTO ON CONFLICT. PostgreSQL usesRETURNING, which was added too recently to SQLite: www.sqlite.org/lang_returning.html - nodejs/sequelize/update_on_duplicate.js:
.bulkCreate({}, { updateOnDuplicate: ['col1', col2'] }. Produces queries analogous to.upsert. This method is cool because it can upsert multiple columns at once. But it is annoying that you have to specify all fields to be updated one by one manually. - stackoverflow.com/questions/29063232/how-to-get-the-id-of-an-inserted-or-updated-record-in-sequelize-upsert/72092277#72092277
- stackoverflow.com/questions/55531860/sequelize-bulkcreate-updateonduplicate-for-postgresql
- Upsert
- nodejs/sequelize/inc.js: demonstrate the
incrementmethod. In SQLite, it produces a statement of type:UPDATE `IntegerNames` SET `value`=`value`+ 1,`updatedAt`='2021-11-03 10:23:45.409 +00:00' WHERE `id` = 3 - nodejs/sequelize/sync_alter.js: illustrates
Model.sync({alter: true})to modify a table definition, answers: stackoverflow.com/questions/54898994/bulkupdate-in-sequelize-orm/69044138#69044138 - nodejs/sequelize/truncate_key.js
- nodejs/sequelize/validation.js: is handled by a third-party library: github.com/validatorjs/validator.js. They then add a few extra validators on top of that.The
args: truething is explained at: stackoverflow.com/questions/58522387/unhandled-rejection-sequelizevalidationerror-validation-error-cannot-create-pr/70263032#70263032 - nodejs/sequelize/composite_index.js: stackoverflow.com/questions/34664853/sequelize-composite-unique-constraint
- nodejs/sequelize/indent_log.js: stackoverflow.com/questions/34664853/sequelize-composite-unique-constraint
- association examples:
- nodejs/sequelize/one_to_many.js: basic one-to-many examples.
- nodejs/sequelize/many_to_many.js: basic many-to-many examples, each user can like multiple posts. Answers: stackoverflow.com/questions/22958683/how-to-implement-many-to-many-association-in-sequelize/67973948#67973948
- ORDER BY include:
- nodejs/sequelize/many_to_many_custom_table.js: many-to-many example, but where we craft our own table which can hold extra data. In our case, users can like posts, but likes have a integer weight associated with them. Related threads:
- nodejs/sequelize/many_to_many_same_model.js: association between a model and itself: users can follow other users. Related:
- nodejs/sequelize/many_to_many_same_model_super.js
- nodejs/sequelize/many_to_many_super.js: "Super many to many": sequelize.org/master/manual/advanced-many-to-many.html This should not exist and shows how bad this library is for associations, you need all that boilerplate in order to expose certain relationships that aren't otherwise exposed by a direct
hasManywith implicit join table.
- nested includes to produce queries with multiple JOIN:
- nodejs/sequelize/nested_include.js: find all posts by users that a given user follows. Answers: stackoverflow.com/questions/42632943/sequelize-multiple-where-clause/68018083#68018083
- nodejs/sequelize/nested_include_super.js: like nodejs/sequelize/nested_include.js but with a super many to many. We should move this to nodejs/sequelize/many_to_many_super.js.
- two relationships between two specific tables: we need to use
as:to disambiguate them- nodejs/sequelize/many_to_many_double.js: users can both follow and like posts
- nodejs/sequelize/one_to_many_double.js: posts have the author and a mandatory reviewer
- hooks
- internals:
- nodejs/sequelize/common.js: common utilities used across examples, most notably:
- to easily setup different DBRM
- nodejs/sequelize/min_nocommon.js: to copy paste to Stack Overflow
- nodejs/sequelize/min.js: template for new exapmles in the folder
- nodejs/sequelize/common.js: common utilities used across examples, most notably:
Transaction retries are inevitable, as some sQL isolation levels
Doesn't seem to have any simple built-in mechanism?
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