The hard part then is how to make any predictions from it:
- 2024 www.nature.com/articles/d41586-024-02935-z Fly-brain connectome helps to make predictions about neural activity. Summary of "Connectome-constrained networks predict neural activity across the fly visual system" by J. K. Lappalainen et. al.
2024: www.nature.com/articles/d41586-024-03190-y Largest brain map ever reveals fruit fly's neurons in exquisite detail
As of 2022, it had been almost fully decoded by post mortem connectome extraction with microtome!!! 135k neurons.
- 2021 www.nytimes.com/2021/10/26/science/drosophila-fly-brain-connectome.html Why Scientists Have Spent Years Mapping This Creature’s Brain by New York Times
That article mentions the humongous paper elifesciences.org/articles/66039 elifesciences.org/articles/66039 "A connectome of the Drosophila central complex reveals network motifs suitable for flexible navigation and context-dependent action selection" by a group from Janelia Research Campus. THe paper is so large that it makes eLife hang.
Research consortium investigating the drosophila connectome.
Homepage: flywire.ai
The Neurokernel Project aims to build an open software platform for the emulation of the entire brain of the fruit fly Drosophila melanogaster on multiple Graphics Processing Units (GPUs).
Bibliography:
- www.nature.com/articles/d41586-023-02559-9 The quest to map the mouse brain by Diana Kwon (2023)
Grouping their mouse brain projcts here.
Ciro Santilli feels it is not for his generation though, and that is one of the philosophical things that saddens him the most in this world.
On the other hand, Ciro's playing with the Linux kernel and other complex software which no single human can every fully understand cheer him up a bit. But still, the high level view, that we can have...
For now, Ciro's 2D reinforcement learning games.
By cranks:
- www.thehighestofthemountains.com/ has some diagrams. It is unclear how they were obtained, except that they were made over the course of 5 years by a "Space Shuttle Engineer", classic crank appeal to authority. The author belives that brain function is evidence of intelligent design.
- 86 billion neurons www.pnas.org/doi/10.1073/pnas.1201895109
- 1,000 trillion arxiv.org/abs/1906.01703
atlas.brain-map.org/ omg some amazing things there.
www.nature.com/articles/d41586-023-02600-x
They overreached it seems.
Almost since it began, however, the HBP has drawn criticism. The project did not achieve its goal of simulating the whole human brain — an aim that many scientists regarded as far-fetched in the first place. It changed direction several times, and its scientific output became “fragmented and mosaic-like”, says HBP member Yves Frégnac
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