Arterial pressure wave

A small pressure disturbance in an elastic artery propagates through the coupled inertia of blood and compliance of the wall. If $\mathcal{A}$ is the undisturbed area, $\rho$ the mass density and $c$ the wave speed, the linearized equations give $c^2=\mathcal{A}/\rho dp/d\mathcal{A}$. A travelling pressure amplitude $p_{+}$ carries flow amplitude $\mathcal{A}{p}_{+}/(\rho c)$; the oppositely travelling wave has the opposite flow sign.

At a lossless vascular junction, pressure continuity and volumetric flow rate balance give $1+r=t$ and $Y_1(1-r)=Y_{d}t$, where $Y_d$ is the sum of daughter characteristic admittances of an arterial wave. Eliminating transmission amplitude $t$ gives the displayed reflection coefficient. A decrease in total area yields positive reflection if parent and daughter wave speeds are equal; differing stiffnesses require comparison of the admittances rather than areas alone.

For incident and reflected harmonic arterial pressure waves with real $0<r<1$, the local pressure and flow phasors are proportional to $1+r{e}^{-i\vartheta }$ and $1-r{e}^{-i\vartheta }$. Their maximum-time difference is the displayed phase lag, on the branch $0<\vartheta <\pi$. Here $\vartheta =2\omega d/c$ is the round-trip phase to the reflector. Its derivative has the sign of $\cos \vartheta$. Raising the wave speed reduces the lag when $0<\vartheta <\pi /2$, but increases it when $\pi /2<\vartheta <\pi$. This conditional harmonic model does not establish an age trend for arbitrary vascular geometry or measurement stations beyond the sole reflector.

A hydraulic resistance $R$ imposes $q=p/R$. Combining this with forward and backward arterial pressure waves, $p=p_{+}+p_{-}$ and $q=Y(p_{+}-p_{-})$, gives the displayed reflection coefficient. A matched load $RY=1$ has no reflected pressure wave, while a closed end has reflection coefficient one. At a network junction the combined downstream input admittance replaces $1/R$.

For time dependence $e^{i\omega t}$ and a segment of length $\ell$, let $\beta =\omega \ell /c$. Adding the forward and backward arterial pressure waves gives the displayed upstream-to-downstream matrix. The flow orientation is downstream at both ends. At a junction, pressure is continuous and incoming volumetric flow rates balance outgoing ones.

Consider two identical two-segment paths from an inlet to a distal junction, with equal resistive beds at the two intermediate junctions and the distal junction. The segment transfer matrix and junction flow balances determine all pressures. If one inlet branch is removed and the beds are weakly loading the waves, the remaining segments form a three-segment chain with an effectively closed far end. The altered reflection pattern can raise peripheral oscillatory flow amplitudes even though a branch was lost; the incident wave amplitude, rather than total inlet pressure or flow, is the prescribed forcing.

The characteristic admittance of an arterial wave relates the volumetric flow rate of a travelling arterial pressure wave to its pressure. For forward and backward amplitudes, $p=p_{+}+p_{-}$ and $q=Y(p_{+}-p_{-})$. It is the reciprocal of characteristic pressure-to-flow impedance, and should not be confused with the reciprocal hydraulic resistance of a steadily resistive segment.