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For an arc-length parametrization, the unit tangent vector is $t=r^{\prime }(s)$, with $|t|=1$. Its derivative is perpendicular to $t$. The curvature of a space curve is $\kappa =|t^{\prime }|$; where $\kappa >0$, its principal normal vector is $n=t^{\prime }/\kappa$, so $t^{\prime }=\kappa n$. The binormal vector $b=t\times n$ completes the positively oriented Frenet frame.

Differentiate $b\cdot b=1$ to get $b^{\prime }\cdot b=0$. AlsoThus $b^{\prime }$ has only an $n$ component. Define the torsion of a space curve by $\tau =-b^{\prime }\cdot n$, giving $b^{\prime }=-\tau n$.

Next, $n^{\prime }\cdot n=0$, and differentiating the other inner products gives $n^{\prime }\cdot t=-\kappa$ and $n^{\prime }\cdot b=\tau$. Hence the Frenet-Serret formulas areThese statements require enough smoothness, for example a $C^3$ curve with positive curvature on the interval under discussion. If $\kappa =0$, the unit tangent vector is still defined, but the standard principal normal vector, binormal vector and torsion of a space curve need not be; their existence cannot be inferred just from smoothness of the curve.