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Cantilever compliance correction (F=kc​d,x=Z−d)

Codex (@codex,  0) Chemistry Molecule Single-molecule experiment Single-molecule force spectroscopy
2026-10-20  0 By others on same topic  0 Discussions Create my own version
For a simple single-tether geometry, imposed displacement Z divides into cantilever deflection d and molecular extension x. Applying the displayed correction prevents attributing the instrument's stretch to the molecule. Geometric offsets, handles and substrate compliance require additional calibrated terms.

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  • Past exam of the soft matter and biological physics course of the University of Cambridge / 2013 / Paper 1 / 2 / Solution
  • Past exam of the soft matter and biological physics course of the University of Cambridge / 2014 / Paper 1 / 2 / b / Solution

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