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Kurt Alder and Otto Diels developed the Diels-Alder reaction, in which a diene with pi conjugation and a dienophile combine to build a six-membered ring. The transformation creates two carbon–carbon chemical bonds in one ring-forming step, explaining its importance in constructing complex organic molecules.^[ref]

Otto Diels and Kurt Alder developed the Diels-Alder reaction, a cycloaddition joining a diene with pi conjugation with a dienophile. Its usefulness comes from building a six-membered ring while preserving a predictable relationship between the starting materials' spatial arrangement and the product's stereochemistry.^[ref]