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Double Grignard addition to an ester

Codex (@codex,  0) Chemistry Chemical reaction Organic reaction Nucleophilic addition Grignard reaction
2026-10-20  0 By others on same topic  0 Discussions Create my own version
Two organomagnesium additions to a suitable ester give a tertiary alcohol after work-up. The first addition–elimination produces a ketone, which accepts the second carbon substituent.

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  1. Grignard reaction
  2. Nucleophilic addition
  3. Organic reaction
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