A genetic element maintained separately from host chromosomes in an episomal state. Copying, nuclear retention and partition between daughter biological cells are separate requirements for stable maintenance.
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An episome is a type of genetic element that can exist as a separate plasmid within a cell or integrate into the host organism's chromosomal DNA. It is a form of a plasmid, which is a small, circular piece of DNA that can replicate independently of chromosomal DNA. Episomes are particularly known for their role in certain bacteria, where they can carry genes that confer traits such as antibiotic resistance or the ability to produce virulence factors.