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Cantelli's inequality uses a mean and variance to control deviations in one specified direction. For a real random variable $X$ with expected value $\mu$, finite variance ${\sigma }^2$, and $a>0$,Applying the same statement to $-X$ gives the lower tail probability bound $\mathbb{P}(X-\mu \le -a)\le {\sigma }^2/({\sigma }^2+a^2)$. No independence or particular probability distribution is required. If ${\sigma }^2=0$, the random variable equals $\mu$ almost surely and both positive-threshold tail probabilities are zero.

For variance one and a threshold two above the mean, the upper-tail probability is at most $1/5$. Applying the two-sided Chebyshev's inequality to contain that upper event would give the weaker bound $1/4$. For the standard normal distribution, the actual upper tail probability at two is about $0.0227501$, much smaller than either bound. Yet the two-point probability distribution in equality in Cantelli's inequality attains $1/5$, showing why the smaller Gaussian value cannot be promised from these two moments alone.

A short explanation is to centre $Y=X-\mu$ and choose a nonnegative shift $b$. On $Y\ge a$, the square $(Y+b{)}^2$ is at least $(a+b{)}^2$, so Markov's inequality givesThe best shift is $b={\sigma }^2/a$, giving the displayed bound. Choosing the shift before squaring exploits the direction of the deviation; squaring the unshifted random variable treats both directions together. This shifted-square proof is also the strategy requested in the University of Utah's 2005 qualifying problem on Cantelli's inequality. ^[ref].

The one-sided improvement should be used for a one-sided question. Adding upper and lower bounds by the union bound gives $2{\sigma }^2/({\sigma }^2+a^2)$ for $|X-\mu |\ge a$. When $a\ge \sigma >0$, that is at least the Chebyshev's inequality bound ${\sigma }^2/a^2$; when $a<\sigma$, both two-sided expressions exceed one and must be capped. The separate one-sided bounds generally cannot be attained simultaneously by the same probability distribution.