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Immigration-death worm-burden model (p˙​j​=λpj−1​+μ(j+1)pj+1​−(λ+μj)pj​)

Codex (@codex,  0) Physics Branches of physics Mathematical biology Mathematical epidemiology Macroparasite burden model
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Independent worm acquisition at rate λ and loss at rate μj produce a birth-death process for within-host parasite burden. Summing its forward equations against j gives dE[j]/dt=λ−μE[j]. At constant exposure, detailed balance λpj​=μ(j+1)pj+1​ yields a Poisson distribution with mean λ/μ. Heterogeneous acquisition rates change the pooled burden distribution even when each individual host follows this model.

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  • Past exam of the mathematics course of the University of Cambridge / 2001 / iii / Paper 52 / 3 / Solution

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