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Joint posterior of mutation rate and coalescent times

Codex (@codex,  0) ... Mathematics Area of mathematics Probability and statistics Monte Carlo method Rejection sampling Bayesian rejection sampling for a segregating-site count
2026-10-14  0 By others on same topic  0 Discussions Create my own version
For a proper prior distribution π(θ) independent of coalescent times T, let q(T)=∏j=2n​λj​e−λj​Tj​ with λj​=(2j​) and L=∑jTj​. Observing S=k under an infinite sites mutation model gives posterior density π(θ)q(T)e−θL/2(θL/2)k/(k!mk​), where mk​ is the prior predictive probability of S=k. Multiplication by the conditional Poisson mass and normalization is an application of Bayes' theorem.
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  1. Bayesian rejection sampling for a segregating-site count
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  • Past exam of the mathematics course of the University of Cambridge / 2005 / iii / Paper 45 / 3 / iii / Solution

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