Geneticist who, with Esther Lederberg, developed replica plating to investigate bacterial mutants. Preserving the spatial pattern of colonies allowed selection to reveal variants that already existed before exposure.[ref]
Replica plating and indirect selection of bacterial mutants by Joshua Lederberg and Esther Lederberg. Title, author list and reported study
Portrait of Joshua Lederberg
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Joshua Lederberg (1925–2018) was an American microbiologist renowned for his pioneering work in the fields of genetics and microbiology. He made significant contributions to our understanding of bacterial genetics, particularly concerning recombination and the mechanisms of gene transfer in bacteria. Lederberg was awarded the Nobel Prize in Physiology or Medicine in 1958, which he shared with George Beadle and Edward Tatum for their discovery that genes act by regulating definite chemical events.