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Muscle tissue is tissue specialized for force generation through contractile proteins. Skeletal, cardiac and smooth muscle differ in organization and control. Tissue-level output also depends on supporting matrix and transmission of force between cells and attachments.

Death of heart-muscle tissue due to inadequate blood supply. It is a tissue injury, distinct from reversible ischaemia and from cardiac arrest, although either can accompany it.

Skeletal muscle is striated muscle tissue organized into long multinucleate fibers and supporting connective tissues. Neural activation recruits force that is transmitted to attachments. Its output depends on fiber properties, recruitment and mechanical loading, not only the amount of muscle present.