A cell-surface protein whose phosphorylated intracellular region can recruit signalling adaptors.
In kidney podocytes, it is a component of the specialized filtration-slit architecture. Its intracellular signalling interactions can recruit Nck and actin-regulatory partners, connecting a membrane contact to cytoskeletal organization. [ref]

Ancestors (5)

  1. Membrane protein
  2. Cell membrane
  3. Biological cell
  4. Biology
  5. Home

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